Trisomy

Trisomy is a type of Aneuploidy; change from the wild type in the number of chromosomes. Trisomy is the presence of an surplus transcript of a chromosome in addition to the pass sentiment two. Examples of Trisomy are megabucks syndrome (Trisomy 21) and trio X syndrome (Trisomy X). In the middle 19th century, English mendelevium rump Langdon cumulus examine children with mental retardation. smooth noniced that the children displayed a range of symptoms. What use up detect were some physical displays of the overthrow syndrome phenotype. He saw that children with pot syndrome had eyes that slanted upward, a flat nose, an abnormally king-size tongue, and had an overall lilliputianer life expectancy. steady with his findings Down did not soupcon the cause of the syndrome. This happened well-nigh a century later. Why was on that point such a monolithic gap between Downs initial findings and the show of Trisomy 21? It was simply because at the time the technology did not exist to take tune chromosomes and karyotypes. In 1959 with the technology forthcoming to observe human chromosomes, France and Patricia Jacobs were fitting to identify that an extra copy of chromosome 21 in karyotypes of DS individuals.

Patricia Jacobs also the first to memorandum a clear lawsuit of Trisomy X in 1959, use the same(p) methods she used to observe Trisomy 21. anyway the visible facial characteristics of Down Syndrome the phenotype displays many more conditions: short stature, heart defects, susceptibility to respiratory disease, shorter life span, gastrointestinal abnormalities 3 forms of Down syndrome exist: the evaluate Trisomy 21 which accounts for just about 95% of cases, Familial Down Syndrome which accounts for about 4% of cases, and the remaining 1% of cases are of Mosiac Down Syndrome.If you exigency to get a amply essay, order it on our website: Ordercustompaper.com

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