Blood pressure Essay Example for Free

Blood pressure Essay Question One: Hypertension (in addition to a number of medical conditions) may be considered as primary or secondary. Explain these concepts giving three examples of secondary hypertension and their pathophysiology. Most of the conditions that cause secondary hypertension involve the overproduction of one of the bodys hormones. Some of the medical problems that can cause secondary hypertension include: Kidney disease. Secondary hypertension is related to damaged kidneys or to an abnormal narrowing of one or both renal arteries. The renal arteries are the major blood vessels that bring blood to each kidney. When the kidneys blood supply is reduced by a narrowing (called renal artery stenosis), the kidney produces high levels of a hormone called renin. High levels of renin trigger the production of other substances in the body that raise blood pressure, particularly a molecule called angiotensin II. Adrenal disease. The adrenal glands sit on top of the kidneys and produce several hormones that help regulate blood pressure. Sometimes, one or both adrenal glands make and secrete an excess of one of these hormones. Three different types of adrenal gland conditions cause high blood pressure: Pheochromocytoma. A tumour of the adrenal gland that overproduces the hormones epinephrine (adrenalin) and norepinephrine (noradrenalin). Hyperaldosteronism (also called Conns syndrome). Both adrenal glands can overproduce the salt-retaining hormone aldosterone or it can arise in a benign adrenal tumour. Hypercortisolism (also called Cushings syndrome). Both adrenal glands can overproduce the hormone cortisol or it can arise in a benign or malignant tumour. Hyperparathyroidism. A hormone called parathormone is made by four tiny glands in the neck called parathyroid glands. If the glands produce too much hormone, calcium levels in the blood increase. People with hyperparathyroidism are more likely to have high blood pressure. The exact reason for this association is not known. Question Two: Roger was a symptomatic and only came in for a check up. Why is it important for this silent disease to be detected and appropriately treated? As blood flows through arteries it pushes against the inside of the artery walls. The more pressure the blood exerts on the artery walls, the higher the blood pressure will be. The size of small arteries also affects the blood pressure. When the muscular walls of arteries are relaxed, or dilated, the pressure of the blood flowing through them is lower than when the artery walls narrow, or constrict. Blood pressure is highest when the heart beats to push blood out into the arteries. When the heart relaxes to fill with blood again, the pressure is at its lowest point. Blood pressure when the heart beats is called systolic pressure. Blood pressure when the heart is at rest is called diastolic pressure. When blood pressure is measured, the systolic pressure is stated first and the diastolic pressure second. Blood pressure is measured in millimeters of mercury (mm Hg). For example, if a persons systolic pressure is 120 and diastolic pressure is 80, it is written as 120/80 mm Hg. The Ameri can Heart Association has long considred blood pressure less than 140 over 90 normal for adults. However, the National Heart, Lung, and Blood Institute in Bethesda, Maryland released new clinical guidelines for blood pressure in 2003, lowering the standard normal readings. A normal reading was lowered to less than 120 over less than 80. Hypertension is a major health problem, especially because it has no symptoms. Many people have hypertension without knowing it. In the United States, about 50 million people age six and older have high blood pressure. Hypertension is more common in men than women and in people over the age of 65 than in younger persons. More than half of all Americans over the age of 65 have hypertension. It also is more common in African-Americans than in white Americans. Hypertension is serious because people with the condition have a higher risk for heart disease and other medical problems than people with normal blood pressure. Serious complications can be avoided by getting regular blood pressure checks and treating hypertension as soon as it is diagnosed. If left untreated, hypertension can lead to the following medical conditions: arteriosclerosis, also called atherosclerosis heart attack stroke enlarged heart kidney damage. Arteriosclerosis is hardening of the arteries. The walls of arteries have a layer of muscle and elastic tissue that makes them flexible and able to dilate and constrict as blood flows through them. High blood pressure can make the artery walls thicken and harden. When artery walls thicken, the inside of the blood vessel narrows. Cholesterol and fats are more likely to build up on the walls of damaged arteries, making them even narrower. Blood clots also can get trapped in narrowed arteries, blocking the flow of blood. Arteries narrowed by arteriosclerosis may not deliver enough blood to organs and other tissues. Reduced or blocked blood flow to the heart can cause a heart attack. If an artery to the brain is blocked, a stroke can result. Hypertension makes the heart work harder to pump blood through the body. The extra workload can make the heart muscle thicken and stretch. When the heart becomes too enlarged it cannot pump enough blood. If the hypertension is not treated, the heart may fail. The kidneys remove the bodys wastes from the blood. If hypertension thickens the arteries to the kidneys, less waste can be filtered from the blood. As the condition worsens, the kidneys fail and wastes build up in the blood. Dialysis or a kidney transplant are needed when the kidneys fail. About 25% of people who receive kidney dialysis have kidney failure caused by hypertension. Question Three: The renin-angiotensin system plays a central role in blood pressure regulation. Explain the renin-angiotensin system with reference to Conns syndrome. The Renin-Angiotensin-Aldosterone System is a hormone system that regulates BP and fluid balance. When blood volume is low, the juxtaglomerular cells in the kidneys secrete Renin directly into circulation. Plasma Renin converts a polypeptide called Angiotensinogen, which is secreted from Liver into Angiotensin I, which in turn is converted to Angiotensin II (or ATII) by the enzyme called ACE (Angiotensin converting enzyme) found in the lungs. It so happens that Angiotensin II is a potent vaso-active peptide that causes blood vessels to constrict, resulting in increased blood pressure. Angiotensin II also stimulates the secretion of the hormone Aldosterone from Adrenal cortex. Aldosterone causes the tubules of the kidneys to increase the reabsorption of sodium and water into the blood. This increases the volume of fluid in the body, which also increases blood pressure. If the renin-angiotensin-aldosterone system is too active, blood pressure will be too high. There are many drugs that interrupt different steps in this system to lower blood pressure. These drugs are one of the main ways to control HBP, heart failure, renal failure and the harmful effects of Diabetes. Angiotensin II is degraded to angiotensin III by angiotensinases located in red blood cells and the vascular beds of most tissues. Angiotensin III has 40% of the pressor action of ATII, but 100% of the aldosterone-producing activity of ATII. Angiotensin II has autocrine, paracrine and endocrine actions on different systems: Cardiovascular effects: AT II is the most powerful vasopressor known, constricting both arteries and veins. Myocyte growth is stimulated through a local tissue RAAS. The same system can be activated in the smooth muscle cells in conditions of HTN or endothelial damage thus contributing to and accelerating the process of Atherosclerosis. Neurological effects: ATII increases the thirst sensation by directly stimulating the Subfornical organ of the brain (Dipsogenic action). AT II also decreases the response of Baroreceptor reflex. ATII increases secretions of both ADH and ACTH besides stimulating postganglionic sympathetic fibers to secrete Noradrenaline. Adrenal effects: Angiotensin II acts on the Adrenal cortex causing it to release Aldosterone, a hormone that causes the kidneys to retain sodium and lose potassium.

Christian Rhetoric in The History of Mary Prince and Second Class Citiz

Christian Rhetoric in Mary Prince’s The History of Mary Prince, and Buchi Emecheta’s Second Class Citizen It is true, perhaps, that women are the subset of humanity whose rights had been the longest stripped of them, and who had been abused the worst and for the longest time. Even today, many people believe that women still do not have the equality that ought to be afforded them. Since women first started making steps to approach that ideal equality, they have used various means, including literature, to further their cause. Both Mary Prince’s The History of Mary Prince, as well as Buchi Emecheta’s Second Class Citizen, use language of Christian rhetoric to simultaneously cast their characters and themselves as sinners and the redeemed and righteous as well as portraying the journey of redemption between one and the other. This subconscious wording engenders fellowship in their readers, who can relate to the story of the redeemed, and who exist in an overwhelmingly moral and Christian society. The use of Christian rhetoric as a means to instill empathy in the reader is first and foremost evident in the specific language of the texts. The word choice of the author subtly highlights Christian ideals with direct relevance to the author and character herself. For example, Prince recalls a time after the white slave owners pulled down the slaves’ prayer shed, saying, â€Å"A flood came down soon after and washed away many houses, filled the place with sand and overflowed the ponds: and I do think that this was for their wickedness; for the Buckra men there were very wicked† (Prince 19). Prince’s use of the word wickedness here implies some sort of tie to Christianity. There is a vast array of words that could fit in the place of â€Å"wic... ...to view the writer’s work as in concert with Christian ideals and ideology, therefore establishing, in the mind of the reader, a thorough connection between the writer and their cause, and what the reader perceives, most likely, as moral and good. This holds true especially in Mary Prince’s The History of Mary Prince, as well as Buchi Emecheta’s Second Class Citizen, both of who use Christian rhetoric in a subconscious, literal, and in the case of Prince, plot-oriented manner. This causes their respective audiences to see them and their causes, through their characters, as righteous, therefore successfully fulfilling the purpose of using such language. Works Cited Emecheta, Buchi. Second-class Citizen. New York: G. Braziller, 1975. Print. Prince, Mary. The History of Mary Prince: a West Indian Slave Narrative. Mineola, N.Y.: Dover Publications, 2004. Print.

Kant’s Ethics of Dignity and Freedom Essay

Immanuel Kant’s moral philosophy contends that morality is grounded from deductive reasoning.   In his Groundwork for   Metaphysics of Morals, Kant introduced the main premise of his moral Philosophy, the Categorical Imperative (Singer, 1993).   The Rationale of Kantian ethics is to construct ethical principles in accordance with rational procedures which includes duty (Singer, 1993).  Ã‚  Ã‚   Kant grounds his moral philosophy on the question â€Å"what I ought to do?†, he then attempts to determine the fundamental principles that humans should adopt.   Kant fully furnishes his ethical claims in a subjective approach regarding what is good for man. Criticism of Previous Ethical Thories In his Critique of Pure Reason, Immanuel Kant primarily makes a connection between rationalism and empiricism.   Conversely, Kant counters David Hume’s empiricism, stating that although all knowledge begin with experience, it does not necessarily mean that it all comes from experience.   In his realization of Hume’s dubious conclusions, Kant dwelled on the postulation that all ideas are representations of sensory experience (Guyer and Wood, 1998).   To counter Hume, Kant attempted to find another means to derive cause and effect without dependence from empirical knowledge (Guyer and Wood, 1998). Kant grounds his perspective of freedom as autonomy, and morality from the beliefs of renowned French enlightenment philosopher, Jean Jacque Rousseau.   Rousseau believes that freedom is not simply being unbound from any law, but by the laws that are, in a sense,   made by the individual.   Hence, Kant primarily conforms to the idea that freedom bypasses the negative notion of being free from influences that are governed by elements outside the self (Johnson, 2004). Kant, although influenced by rationalist Rene Descartes, counters the latter’s perspective on the existence of God based on reason, that due to restrictions brought about by reason, no one can really know if there really is a God.   Kant solidifies his claims by stating that justifiable knowledge must be grounded from a reality encountered solely by human experience (Singer, 1993).   In his explanation, Kant asserts that all the preparations for reason in what may be deemed as pure philosophy, are directly adressed to three problems; God, soul and freedom (Guyer and Wood, 1998).   Kant neither denies nor accepts the existence of God, he, however, argues against the rationalist perspective of God and sees the Christian scriptures as a worldly narrative which can be agreed upon as a representation of morality (Singer, 1993). Autonomy and Heteronomy Autonomy and its principles are important in Kant’s moral philosophy, this is due to the fact that the basis of the actions are based on internal motives.   In this context, the one who acts (the Agent) does it in an autonomous manner since the agent is the only key holder to the basis of the action.   Heteronomy, for Kant is an element in the basis of a moral act that are driven by external factors (Singer, 1993).   A person then who acts under the influence of outside forces is not acting freely, therefore, that person is acting heteronomously. Categorical Imperative Kant grounds the foundations of the princple of his moral philosophy from the denial of principles that are non-universalizable.   Kant formulates this concept as a demand which he calls the categorical imperative (Singer, 1993).   Kant’s formulation of the categorical imperative claims that Act only according to that maxim whereby you can at the same time will that it should become a universal law   (Singer, 1993).   This sentiment is the core of Kant’s ethics and is the basis for the maxims or fundamental principles an individual may advocate.    Kant’s categorical imperative may also be viewed as an end in itself, described as a means that only serves the fulfillment of the interest itself and not to any other purpose.   Immanuel Kant holds that the principles of reason governs the moral law and that irrelevant factors such as what would make people happy, is the basis of morality and the moral law (Guyer and Wood, 1998).   Kant defining Rational beings as people who are capable of moral deliberation who can choose to act by fundamental principles that have universality.   It is in this framework that Kant formulated the Kingdom of Ends and furthered his Categorical Imperative, implying the term kingdom as a group of rational beings bound by common laws. Kant argues that inclination to the categorical imperative bequeaths an individual with autonomous ethical choice.   The basis for such argument is on Kant’s assertion of the bond between moral law and autonomy.   In his presupposition, Kant suggests that practical will is bound by the categorical imperative through the simple fact of reason, and uses such thought to postulate that our wills are autonomous (Johnson, 2004). The essence of Kant’s moral philosophy is quite ironic due to the primary intentions that are never achieved. The first point of criticism is that Kant, like many other scholars are in pursuit of a universal truth, given the textual fact that Kant’s ideas are based on his own assumptions, it is unimaginable that Kant is unable to provide concrete defense of autonomy of the will in accordance to the categorical imperative. Reflection In reference to his categorical imperative, Kant provokes individuals to act according to such principles that ends to the universal law (Singer, 1993).   This categorical imperative, and his moral beliefs for that matter, are based on subjective thinking, another irony on the true aims of his moral philosophy.   In this regard, I think it is safe to connote that Kant’s undertaking of how an individual should think only provides signs of the conventional human flaw, the fear of elements and concepts that the human brain cannot fully comprehend. Personally, I think Kant’s suggestion regarding compliance to the categorical imperative provides freedom in ethical decision making is incomprehensible, since one of his underlying concepts is rationality and morality (Singer, 1993).   I feel that Kant’s moral philosophy may result to individuals to be narrow-minded since they only consider the reasons in doing actions and overlook the possible outcomes that may have destructive tendencies.   I myself cannot see how to live in a world of subjectivity and apathy.   If Kant wrote his ethical theories to burst out personal opinion, he should have been a journalist, rather than a scholar who cannot live up to the principles of his own philosophy. References Johnson, R. (2004). Kant’s Moral Philosophy. Stanford Encyclopedia of Philosophy.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Retrieved 12 February 2008 from http://plato.stanford.edu/entries/kant-moral/#Aut Singer, P. (Ed.) (1993). Blackwell companions to philosophy: A companion to ethics. Malden,   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   MA: Blackwell Publishing. Kant, I., Guyer, P. & Wood, A. (Eds.). (1998). Critique of Pure Reason. Cambridgeshire:   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   Cambridge UP.

Individual Assessment Cover Sheet / Plagiarism Declaration...

Individual Assessment Cover Sheet / Plagiarism Declaration Form This form must be completed and included with each assessment you submit for marking to the School. Although this assessment is submitted electronically, you must still complete and include this form with your assessment. Student Number: 201413649 Unit Code No.: MHE613 Unit Title: Conventions Management Assessment No.: 3 Lecturer: Ms Rajka Presbury Submission Date: 25th March, 2016 Declaration: I have read the School’s Policy on Plagiarism and Improper Conduct and all the materials pertaining to plagiarism. I declare that, to the best of my knowledge and belief, this assessment is my own work, all sources have been properly acknowledged, and the assessment contains no plagiarism. I further declare that I have not previously submitted this work or any version of it for assessment in any other unit or award offered by the School, or any other institution, without first ensuring that an explicit provision has been made and that I have obtained written permission from the Deputy Head of School for doing so. (Documentation supporting this provision MUST be attached.) I have submitted this assessment to Turnitin.com and I am aware that the School may act upon the Turnitin result, to determine whether an incident of plagiarism has occurred. You will be deemed, in effect, to have signed this form when you hit the ‘Send’ or ‘Submit’ button to submit your assessment for marking.Show MoreRelatedIndividual Assessment Cover Sheet / Plagiarism Declaration Form Essay1370 Words   |  6 PagesIndividual Assessment Cover Sheet / Plagiarism Declaration Form This form must be completed and included with each assessment you submit for marking to the School. 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